I’m open sourcing my health logs and data in my journey to recover from Long COVID/ME in the hope that it will help others fighting the same fight.

• Age: 39
• Twitter: https://twitter.com/liamsLCjourney
• Website: LC/ME on liamrosen.com
• Email: [email protected]
• Location: Lower East Side of Manhattan, New York City
• Background: Former semi-professional athlete, stereotypical über-healthy pre-Long COVID lifestyle (heavy lifting, whole foods diet, no drugs/non-drinker)

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Current Plan (August 2026)

Since mid-January 2026, I have been in a severe, 24/7 bedbound crash which started after GI issues from an adverse reaction to microdosed tirzepatide.

I do not believe I will be recovering from this crash naturally. I will need to find something to achieve the next goal: get out of bed.

Strategies

With the rapid progress of AI, I have become more and more convinced that the answer to everything is to collect more data. I am continuing to get as much testing as possible.

I am in a bit of a lull at the moment in terms of cracking my case. I hope to make great strides by analyzing my Amatica data (expected late September).

Interventions:

Low dose Abilify doing well - at 0.3mg/day, up from 0.05mg/day starting March 12, phone and laptop tolerance has increased, light tolerance has increased massively, feeling less physical “weight”

Started weekly low-dose rapamycin at the beginning of June. Since I started, my PEM episodes seem to be shorter and less intense.

My cytokine panel came back with a clear chemokine and adhesion signal (IL-8 at 7.6x) while every conventional inflammatory and T-cell marker was normal. That is the first result in a while that changed my plans. Next up: pravastatin, then either Maraviroc or colchicine.

The same panel was low on the interferon and IL-12 axis, so I have deprioritized baricitinib.

Upcoming Testing

• Amatica RNA
• TLabs Borellia (Lyme)
• ChronicleBio </aside>

Vaccination and infection timeline

• First COVID infection: November 2021 (likely Delta variant)
• Reinfection and “official” Long COVID onset: Early May 2022 (Probably BA.2 or possibly BA.2.12.1 variant - mild infection, recovered in a week, then symptoms began, likely after lifting weights to failure)
• Vaccines: Moderna (April-May 2021), Moderna booster (Dec 2021), Pfizer booster (Nov 2022)
  • Have not gotten vaccines since then for fear of making my condition worse

Episodic pattern

I’ve had a unique episodic pattern in my disease:

• Periodic, often severe PEM crashes with complete 100% recovery between episodes - improvement is nearly immediate, not gradual: full health returns overnight
  • July 2022 - April 2023: 9 months completely symptom-free
  • September 2023 - May 2025: 1.5 years completely symptom-free
  • Triggers: Exercise intolerance, infections, sometimes no clear trigger
• Daily pattern: Worse after naps. Worsening at noon and a further one at 5 PM, improvement in evenings and best at night. Symptoms disappear after sleep deprivation (waking before 6 AM)

Complete episode history

1. Summer 2016 (!): had PEM-like symptoms for 2 months, worked with primary care doctor, never figured it out and they just went away
2. February 2022: three months after first COVID infection - after a long day of walking with a friend, my legs simply turned to jelly - I worried about making it home and **had to crawl up the stairs into my house